Los objetivos de la investigación

Introducción: Un objetivo, es la intención explícita de un investigador de alcanzar un resultado a lo largo de una investigación, son decisivos en un estudio investigativo pues constituyen el eje en torno al cual se diseña la estructura del estudio. Objetivo: Brindar información sobre la redacción de los objetivos en los trabajos de investigación. Métodos: Se realizó una revisión bibliográfica en las bases de datos TESEO, PubMed, Scopus, Latindex, SciELO, Redalycs, Hinari y Dialnet, donde se encontraron documentos que trataron el tema relacionado con los objetivos. Resultados: Se hace referencia a la definición, características, tipos y estructura de los objetivos de investigación, la importancia del alcance de la investigación en su formulación, relación de los objetivos con el problema y el título. Por último, se señalan los errores frecuentes que se repiten en la redacción de los objetivos. Se localizaron 28 publicaciones y se seleccionaron 23 que se consideraron relevantes para la revisión. Se consideró relevante a las publicaciones efectuadas en los últimos cinco años y aquellas que abordaron el tema a profundidad. Conclusiones: Los objetivos son decisivos en un estudio investigativo, su correcta formulación evita desviaciones del proceso y facilita la solución al problema que se investiga.

Introduction: Objectives are an important component to support and guide the implementation of a research proposal. Objective: To provide information about on the most important aspects to writing research objectives. Methods: A review of literature was done in the main database focused aspects related to writing research objectives. Results: Reference is made to definition, components, characteristics, types, and prioritization of research objectives, and the relationship between the research problem, objectives and title. Finally, it was pointed the frequent errors that are repeated in the writing of the objectives. Twenty-eight publications were located and 23 that were considered relevant to the review were selected. Publications made in the last five years and those that addressed the subject in depth were considered relevant. Conclusions: The objectives are decisive in an investigative study, their correct formulation avoids deviations from the process and facilitates the solution to the problem under investigation.

The 100 Most-Cited Papers in Dentin Hypersensitivity: A Bibliometric Analysis

ABSTRACT Objective: To identify the 100 most-cited articles in DH and analyze their characteristics. Material and Methods: A search was performed on the Web of Science (WoS) and the 100 most-cited articles were selected. The following data were extracted: citations, year of publication, authorship, institution, country, journal, language, study design, topic of interest, conflict of interest (COI), and sponsorship. The VOSviewer software was used to visualize bibliometric networks. Poisson regression analysis was performed to measure associations between several citations and the characteristics of the studies. Results: The number of citations ranged from 346 to 48. The most-cited article was published in 1997 by Holland in the Journal of Clinical Periodontology. This journal published the most papers, followed by the Journal of Oral Rehabilitation and Journal of Dentistry. Laboratory research, review, and clinical trial were the study designs most prevalent. Reviews (p<0.05; PR= 1.853) and method development studies (p<0.05; PR= 1.853) had a more chance to present more citations. The main topics of interest were the clinical effectiveness of desensitizers and in vitro analysis of dentin morphology. Sponsorship and COI were underreported. England and USA presented the greatest number of citations and connections in the coauthorship network map. Conclusion: Most of the articles were original research, and their topics of interest were mainly the clinical effectiveness of desensitizing agents and dentin morphology.

Avaliação de validade de um sistema computacional na identificação de estudos duplicados / Evaluación de la validez de un sistema computacional en la identificación de estudios duplicados / Validity assessment of a computational system in the identification of duplicate studies

Resumo Objetivo Avaliar o desempenho do sistema web "Apoio à Revisão Sistemática" quanto à identificação de referências bibliográficas duplicadas, em comparação a outros programas. Métodos Trata-se de uma pesquisa metodológica que avalia o processo automático de identificação de duplicatas do sistema "Apoio à Revisão Sistemática" (versão 1.0), em comparação ao EndNote X9® e Rayyan® , considerando checagem manual como referência. Foi utilizado um conjunto de estudos relacionados a três temas sobre fibrose cística recuperados das bases de dados Pubmed, Embase e Web of Science. Para avaliação de desempenho, utilizaram-se a sensibilidade, especificidade, acurácia e área sob a curva ROC para cada software, em comparação à referência. Resultados As buscas nas bases de dados resultaram em 1332 estudos, sendo 273 (20,5%) verdadeiros duplicados. Em comparação aos dados de referência, o programa "Apoio à Revisão Sistemática" identificou maior proporção de duplicatas verdadeiras do que os demais. Os valores de sensibilidade, especificidade e acurácia do sistema "Apoio à Revisão Sistemática" apresentaram-se acima de 98%. Conclusão e implicações para a prática O sistema "Apoio à Revisão Sistemática" possui alta sensibilidade, especificidade e acurácia para identificação de estudos duplicados, otimizando o tempo e o trabalho dos revisores da área da saúde.

Resumen Objetivo Evaluar el desempeño del sistema web "Apoyo a la Revisión Sistemática" en cuanto a la identificación de referencias duplicadas en comparación a otros programas. Métodos Se trata de una investigación metodológica que evalúa el proceso automático de desduplicación del sistema web "Apoyo a la Revisión Sistemática" (versión 1.0), en comparación al EndNote X9® y Rayyan®, considerando la verificación manual como referencia. Fue utilizado, como ejemplo, un conjunto de estudios relacionados a tres temas sobre fibrosis quística recuperados de las bases de datos Pubmed, Embase y Web of Science. Se analizó la sensibilidad, especificidad, precisión y el área sobre la curva ROC de los programas. Resultados Las búsquedas en las bases de datos dieron como resultado 1332 estudios, siendo 273 (20,5%) verdaderos duplicados. En comparación a los datos de referencia, el programa "Apoyo a la Revisión Sistemática" identificó mayor proporción de duplicados verdaderos que los demás. Los valores de sensibilidad, especificidad y precisión del sistema "Apoyo a la Revisión Sistemática" fueron superiores a 98%. Conclusión e implicaciones para la práctica El sistema "Apoyo a la Revisión Sistemática" posee alta sensibilidad, especificidad y precisión para identificación de estudios duplicados obtenidos a partir de búsquedas en bases de datos en el área de salud, optimizando el trabajo de investigadores. Palabras clave Exactitud de los Datos; Bases de Datos Bibliográficas; Revisión Sistemática; Sensibilidad y Especificidad; Software.

Abstract Objective To evaluate the performance of the Systematic Review Support web-based system for the identification of duplicate records compared with similar software tools. Methods A methodological study was conducted assessing the automated process of de-duplication performed by the Systematic Review Support web-based system (version 1.0) versus the EndNote X9® and Rayyan® systems, adopting hand-checking as the benchmark reference for comparisons. A set of studies on three topics related to cystic fibrosis retrieved from the Pubmed, Embase and Web of Science electronic databases was used for testing purposes. The sensitivity, specificity, accuracy and area under the ROC curve of the software systems were compared to the benchmark values for performance evaluation. Results The database searches retrieved 1332 studies, of which 273 (20.5%) were true duplicates. The Systematic Review Support tool identified a larger proportion of true duplicates than the other systems tested. The sensitivity, specificity and accuracy of the Systematic Review Support tool exceeded 98%. Conclusion and implications for practice The Systematic Review Support system provided a high level of sensitivity, specificity and accuracy in identifying duplicate studies, optimizing time and effort by reviewers in the health field.

Research hotspots and trend analysis of puberty development among children and adolescents from 2013 to 2022 / 中国学校卫生

Objective@#To analyze the hotspots, frontiers, and future research trends related to puberty development among children and adolescents from 2013 to 2022, and to provide a reference for subsequent research related to puberty development.@*Methods@#Data related to puberty development from 2013 to 2022 were retrieved from the Web of Science core collection with the search formula "puberty timing (title) OR puberty development (title) OR pubertal timing (title) OR pubertal development (title) OR puberty timing (abstract) OR puberty development (abstract) OR pubertal timing (abstract) OR pubertal development (abstract)". The CiteSpace was used for visual analysis.@*Results@#A total of 6 684 publications were obtained and an upward trend could be seen in the number of publications in the field of puberty development in the last 10 years. Researchers with a high number of publications were Juul Anders, Brix Nis, and Ernst Andreas, in addition, the United States had the highest number of publications ( 2 125 ) and the highest betweenness centrality (0.23) in this field. In the last decade, research hotspots had focused on the timing of pubertal initiation, biological mechanisms of pubertal development, and sex differences in pubertal development. Research on environmental endocrine disruptors and the mechanisms of pubertal development were at the forefront of research and future research trends.@*Conclusion@#Scholars can refer to the research hotspots and research trends in this field and focus on the issues related to environmental endocrine disruptors and pubertal development mechanisms.

Research hotspots and frontiers of childhood hypertension / 中国学校卫生

Objective@#To analyze the research status, hotspots and frontier progress of hypertension in children in English and Chinese literature, so as to provide reference for the early prevention of hypertension in children.@*Methods@#The Web of Science core collection database and CNKI database were searched to collect the literature related to the study of hypertension in children from 2000 to 2021, and the CiteSpace 5.8.R3 and VOSviewer 1.6.18 visualization tools were used to analyze the literature characteristics including publications, authors, regions, institutional cooperation, research hotspots and frontiers.@*Results@#A total of 22 687 English studies and 4 440 Chinese studies were finally included. According to the analysis results, the number of articles published on hypertension in children was on the rise. The published English articles were mainly University of Toronto and University of Colorado. The main publishing institution of Chinese articles was the First Affiliated Hospital of Peking University. The United States and China took the lead in the number of core journals published in the field of hypertension in children, the United States ranked first in terms of the influence of publications. Keyword co occurrence analysis showed that the high frequency keywords in the English literature included prevalence, risk, obesity, risk factor, body mass index, insulin resistance, overweight, metabolic syndrome, cardiovascular disease and mortality. Chinese high frequency keywords in the literature include obesity, risk factors, adiposis, influencing factors, overweight, prevalence, diabetes, treatment, health education and body mass index. The analysis of keywords showed that 25 burst terms were obtained separately in English and Chinese literature.@*Conclusion@#In recent years, the research interest on hypertension in children continues to grow and keeps updated, with the research scope expanding significantly, regarding obesity, diabetes and cardiovascular diseases.

International research hotspots on suicide prevention and intervention among students in the past decade / 中国学校卫生

Objective@#To explore research hotspots and trends on suicide prevention and intervention among students in the past decade, and to provide a reference for relevant domestic research and practice.@*Methods@#The CiteSpace software was used to visually analyze 1 559 articles on student suicide prevention and intervention in Web of Science core collection database from 2013 to 2022.@*Results@#The number of articles on student suicide prevention and intervention increased from 84 in 2013 to 254 in 2021. Among them, the United States ranked first with 825 articles, and China ranked second with 221 articles. High frequency keywords included risk factors, suicidal ideation, depression and mental health. And high centrality keywords included harm, life, homosexuality and identity. Cluster analysis yielded 17 class groups. By exploring keyword, we found that the popularity of research topics on student suicide prevention and intervention in the past ten years increased rapidly, covering students from different academic backgrouds, which included suicide risk factors and assessment, help seeking for suicide victims, suicide prevention and intervention methods.@*Conclusion@#Learning from international experience, we should strengthen research on student suicide prevention and intervention, pay special attention to the efficeiency of student suicide screening, the gap betweeen the incidence of problems and the rate of help, and try to construct support systems for them.

Impacto científico y temático de la Rev. Cuerpo Méd. HNAAA: un análisis bibliométrico, 2011-2020

Introducción: El Perú posee un gran número revistas de áreas biomédicas, pero solo algunas han logrado visibilizar e indizar sus publicaciones en diferentes medios de indización de alcance global. Objetivo: Analizar las características de publicación de la Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo (Chiclayo) a partir de indicadores bibliométricos. Material y métodos: Estudio descriptivo que analiza 587 registros bibliográficos de los artículos publicados en la revista durante 2011-2020, a partir de indicadores de impacto científico y análisis de términos. Resultados: La mayor producción de artículos corresponde a originales (60%; X̅=66). Los artículos publicados sobre medicina general obtuvieron más impacto en años anteriores. Los temas más frecuentes fueron estudios sobre pacientes de hospitales de Chiclayo, Lambayeque con casos de covid-19. Conclusiones: La Revista del Cuerpo Médico HNAAA se perfila como una publicación seriada de importancia para visibilizar la producción nacional y local por la cobertura temática en especialidades médicas de relevancia regional que publica.

Background: There are several journals about biomedical areas in Peru, however only a few have managed to make their publications avisible and indexed in different global indexing media. Objective: To analyze the main publication characteristics from Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo (Chiclayo) based on bibliometric methods. Material and methods: Descriptive study that analyzes 587 articles published by the journal from 2011 to 2020, based on bibliometric methods and indicators: citations, scientific impact and co-word analysis. Results: Original articles were the highest types of document published (60%; X̅=66). Published research articles on general medicine received more impact in previous years than the recents. Most frequent topic analyzed were studies about patients from hospitals in Chiclayo city (Lambayeque) with covid-19 clinical cases. Conclusion: Revista del Cuerpo Médico HNAAA is emerging as an important serial publication to make local, national, and international production visible due to thematic coverage in relevant medical specialties.

Indicadores bibliométricos: impacto y altmetrics para una evaluación amplia y equitativa de las revistas científicas de Colombia / Bibliometrics Indicators: Impact and Altmetrics for an Extensive and Equitable Assessment of Colombian Scientific Journals / Indicadores bibliométricos: impacto e altmetria para uma avaliação ampla e equitativa das revistas científicas colombianas

La medición y análisis de la calidad de las publicaciones científicas es de fundamental importancia para evaluar el progreso e impacto de investigadores, grupos de investigación y revistas científicas en la comunidad académica y la sociedad (1,2). Tradicionalmente, la evaluación se encomendaba a pares de reconocida trayectoria, idoneidad y prestigio. Sin embargo, para eliminar subjetividades, desde hace varios años se ha recurrido a indicadores bibliométricos que propenden por una calificación mensurable, objetiva y multidimensional (1,3). Los indicadores bibliométricos (IB) pueden definirse como cuantificadores de información bibliográfica, disponible en documentos científicos y académicos, susceptible de ser analizada en términos de producción y consumo (1,2). Existe una variada tipología de IB (1,2) en función del objeto a examinar (investigador, revista o grupo de investigación) y que en algunos casos son transversales a este. Así, los indicadores personales (edad, sexo y antecedentes de los autores) solo aplican a investigadores o grupos, mientras que los de productividad e impacto aplican también a revistas. Para estas, el indicador de productividad (cantidad) y, aún más, el de impacto ("calidad") son rutinariamente empleados para clasificarlas y compararlas con el propósito, cada vez más controversial, de medir su pertinencia y relevancia académica y/o social (4).

Measuring and analyzing the quality of scientific publications is fundamentally important for assessing the progress and impact of researchers, research groups and scientific journals in the academic community and society (1,2). Traditionally, this assessment was entrusted to peers with a recognized track record, eligibility and prestige. However, bibliometric indicators have been used for several years to eliminate subjectivity, which aim at a measurable, objective and multi-dimensional qualification (1,3). Bibliometric indicators (BI) can be defined as quantifiers of the bibliographic information available in scientific and academic documents susceptible to being analyzed in terms of production and consumption (1,2). There is a typological variety of BI (1,2) based on the object to be examined (researcher, journal or research group) and, in some cases, they are cross-sectional to it. In this way, personal indicators (age, gender and background of the authors) only apply to researchers or groups, while productivity and impact also apply to journals. For journals, the productivity (quantity) and, more so, impact ("quality") indicators, are routinely used to classify journals and compare them, with the increasingly controversial purpose of measuring their academic and/or social pertinence and relevance (4).

A medição e análise da qualidade das publicações científicas é de fundamental importância para avaliar o progresso e o impacto de pesquisadores, grupos de pesquisa e revistas científicas na comunidade acadêmica e na sociedade (1,2). Tradicionalmente, a avaliação era confiada a pares de reconhecida trajetória, idoneidade e prestígio. No entanto, a fim de eliminar subjetividades, há vários anos são utilizados indicadores bibliométricos que visam uma qualificação mensurável, objetiva e multidimensional (1,3). Indicadores bibliométricos (IB) podem ser definidos como quantificadores de informações bibliográficas, disponíveis em documentos científicos e acadêmicos, passíveis de análise em termos de produção e consumo (1,2). Existe uma tipologia de IB variada (1,2) dependendo do objeto a ser examinado (pesquisador, periódico ou grupo de pesquisa) e que em alguns casos são transversais a ele. Assim, os indicadores pessoais (idade, sexo e formação dos autores) se aplicam apenas a pesquisadores ou grupos, enquanto os de produtividade e impacto também se aplicam a periódicos. Para estes, o indicador de produtividade (quantidade) e, mais ainda, o indicador de impacto ("qualidade") são rotineiramente utilizados para classificá-los e compará-los com o propósito cada vez mais controverso de medir sua pertinência e relevância acadêmica e/ou social (4).

Systematic Review Support software system: web-based solution for managing duplicates and screening eligible studies / Sistema "Apoio à Revisão Sistemática": solução web para gerenciamento de duplicatas e seleção de artigos elegíveis

ABSTRACT Objective: To describe the main functions of the "Systematic Review Support" web-based system for removing duplicate articles and aiding eligibility analysis during the process of conducting systematic review studies. Methods: The system was developed based on the incremental build model using the Agile methodology. The software is proprietary source code and was published on a proprietary platform. The architecture of the production environment allows the infrastructure used to increase or decrease according to demand. The system functions are presented with insertion of screenshots of the interfaces of the version for personal computers during the simulation of a systematic review. Results: After importing the files containing the abstracts retrieved from the Pubmed, Embase, and Web of Science databases, the system identifies and removes duplicates for later reading and analysis of title and abstract, a stage which can be performed by one or more reviewers independently. After unblinding of reviewers, the decisions on the eligibility of the studies are compared automatically to help the researchers reach a consensus on any disagreements. Results can be filtered and a PDF produced containing the eligible studies. Conclusion: Version 1.0 of the system is available on the web (sysrev.azurewebsites.net) to assist researchers in the initial stages of systematic reviews.

RESUMO Objetivo: Descrever as principais funcionalidades do sistema "Apoio à Revisão Sistemática" na identificação e exclusão de artigos duplicados e no auxílio na análise de elegibilidade durante a condução de estudo de revisão sistemática. Métodos: O sistema foi desenvolvido com base em um modelo de processo incremental, utilizando-se metodologia Ágil. É de código fechado e foi publicado em plataforma proprietária. O ambiente de produção onde o sistema foi implantado possui arquitetura que permite que a infraestrutura utilizada aumente ou diminua conforme a demanda. As funcionalidades foram apresentadas com inserção de imagens das interfaces da versão para computadores, simulando uma revisão sistemática. Resultados: Após a importação dos resumos recuperados nas bases de dados PubMed, Embase e Web of Science, o sistema permite a identificação e eliminação de duplicatas para posterior leitura e análise de título e resumo, etapa que pode ser realizada por mais de um revisor de maneira independente. Após a quebra do cegamento entre os revisores, as respostas sobre a elegibilidade dos estudos podem ser comparadas automaticamente para facilitar a resolução de divergências pelos pesquisadores. É possível filtrar os resultados e gerar um arquivo PDF com os estudos elegíveis. Conclusão: A versão 1.0 do sistema "Apoio à Revisão Sistemática" encontra-se disponível na web (sysrev.azurewebsites.net) para auxiliar pesquisadores nas etapas iniciais de um estudo de revisão sistemática.

A bibliometric analysis of liver disease research articles published by Chinese mainland authors in Gastroenterology & Hepatology journals indexed in Science Citation Index Expanded / 临床肝胆病杂志

Objective To investigate the articles on liver diseases published by authors from China (excluding Hong Kong, Macao, and Taiwan regions) in Gastroenterology & Hepatology journals indexed in Science Citation Index Expanded (SCIE) in 2016-2020, to analyze the bibliographic and citation data of these articles, and to understand the contribution and impact of Chinese scholars in the field of liver disease research in recent years. Methods The data for bibliometric analysis came from the SCIE database and Journal Citation Reports (JCR). The SCIE database was searched for the journal articles published in JCR Gastroenterology & Hepatology journals in 2016-2020, with a title or abstract containing "Liver", "Hepatocellular", "Hepatitis", "Cirrhosis", or "Hepatic" and a publication type of Article. Clinical guidelines were excluded, and the records with the corresponding author's affiliation containing institutions in China (excluding Hong Kong, Macao, and Taiwan regions) were screened out. R package bibliometrix was used to calculate the frequency of citations of included articles by liver disease studies published by Chinese and global authors in the Gastroenterology & Hepatology journals in 2016-2020, and R package DescTools was used to perform the Cochran-Armitage trend test to observe the change in composition ratio. Results In the Q1 Gastroenterology & Hepatology journals in 2016-2020, liver disease studies published by Chinese authors accounted for 9.5%. In recent years, the proportion of liver disease studies published by Chinese authors in Q1 Gastroenterology & Hepatology journals continues to increase from 6.0% to 12.2% ( P < 0.001). Among the liver disease studies published by Chinese authors in Q1 Gastroenterology & Hepatology journals, 79.7% were funded by National Natural Science Foundation of China, and there was no significant change in the proportion of studies funded by National Natural Science Foundation of China and published by Chinese authors in each partition of Gastroenterology & Hepatology journals in 2016-2020. The frequency of citations of included articles by liver disease studies published by Chinese and global authors in the Gastroenterology & Hepatology journals showed that liver disease studies published by Chinese authors had a high impact in both domestic and international academic communities. Conclusion In recent years, there has been a constant increase in the number of liver disease studies published by Chinese authors in high-impact Gastroenterology & Hepatology journals indexed in SCIE, and most of these studies have been funded by National Natural Science Foundation of China. The liver disease studies published by Chinese authors in Gastroenterology & Hepatology journals have been widely recognized by domestic and international academic communities.

Theoretical discussion and countermeasure analysis on the construction of county medical communities in China / 中华医院管理杂志

Objective:To provide reference for the sustainable development of county medical communities through analyzing key issues in the construction of such communities in China.Methods:Such Database websites as CNKI, Wanfang Data and VIP Information were selected to retrieve journal papers and dissertations with the keywords of " county medical community" " county medical alliance" " county medical and health community" and " medical alliance" . The time period ranged from the establishment of the database to December 2021. Content analysis and social network analysis were used to classify and sort key issues of county medical community construction in the included literature, and the descriptive analysis was used for all the data.Results:274 literatures were obtained in this study, 82 high-frequency issues were extracted for the construction process of county medical communities. It was divided into 3 dimensions of service system, operation mechanism and fund guarantee, including 14 items of integration of resources, integrated management, resource intensification, information construction, medical services, medical quality, family doctors, public health, management system, personnel system, salary system, supervision mechanism, medical insurance fund and financial input. The results of social network analysis showed that the top three high-frequency issues of point centrality and intermediary centrality were lack of highly unified information exchange platform (107.00, 514.48), insufficient service capacity of primary medical institutions (61.00, 238.48) and lack of sustainable benefit distribution mechanism (45.00, 192.38).Conclusions:The construction of county medical community covered three aspects: medical service system, operation mechanism and fund guarantee.The shortage of primary medical service capacity, the lack of coordination of an information platform, the general shortage of essential drugs, the imperfect internal assessment and incentive system, the imperfect supervision system and the imperfect medical insurance supporting policy becomed the main roadblocks in building county medical communities in China. In order to promote the sustainable development of county medical community, the authors recommend to further upgrade the county integrated medical service system, perfect the operation mechanism, and strengthen the input into county health care.

Review and updates on physical activity load assessment in preschool children / 中国学校卫生

Abstract@#With the increasing attention paid to preschool physical activity in recent years, physical activity load assessment of preschool children has evolved with the development of theory and the wide application of microelectronic technology. In this paper, relevant literature from PubMed, Web of Science, and CNKI database were collected and analyzed, aiming to provide review and updates on physical activity load assessment in preschoolers. Given the characteristics of children s physical activities, effective measurement methods should be chosen and integrated from these tools, to improve the accuracy and effectiveness of children s physical activity load assessment.

Estrategia de actualización en búsqueda y recuperación de información científica para desarrollar habilidades informáticas / Update strategy in search and retrieval of scientific information to develop computer skills

RESUMEN Fundamento: la utilización de las tecnologías de la información y las comunicaciones en el primer año de la carrera de Medicina constituye una herramienta para desarrollar habilidades informáticas en cuanto a la búsqueda y recuperación de la información en salud. Objetivo: diseñar una estrategia de actualización en búsqueda y recuperación de información científica para desarrollar habilidades informáticas en el primer año de la carrera de Medicina. Métodos: se realizó un estudio de desarrollo en la Facultad de Ciencias Médicas de Holguín, se diseñó una estrategia con tres etapas: planificación, ejecución y evaluación. Para el estudio se seleccionó 220 estudiantes por muestreo aleatorio simple y de forma intencionada, a los profesores principales de las diferentes asignaturas que se imparten en el primer año de la carrera y los profesores de la disciplina Metodología de la Investigación en Salud. Resultados: se diseñó una estrategia de actualización en búsqueda y recuperación de información científica para desarrollar habilidades informáticas, en el primer año de la carrera de Medicina. La planificación para transmitir conocimientos básicos en la utilización del portal de Infomed y sus recursos. La ejecución se materializa con actividades teórico-prácticas referentes a la búsqueda y recuperación de información científica. En la tercera etapa se evalúo la actualización en búsqueda y recuperación de la información científica de forma integral. Conclusiones: con la estrategia se prepara a los estudiantes en la búsqueda y recuperación de la información científica, la cual desarrolla conocimientos y habilidades informáticas, según las exigencias del plan de estudio E en la carrera de Medicina.

ABSTRACT Background: the use of information and communication technologies in the first year of the Medicine career constitutes a tool to develop computer skills in search and retrieval of health information. Objective: to design an update strategy in search and retrieval of scientific information to develop computer skills in the first year of the Medicine degree. Methods: a development study was carried out at the Faculty of Medical Sciences of Holguín; a strategy was designed with three stages: planning, execution and evaluation. A sample of 220 students was selected by simple random sampling and intentionally, to the main teachers of the different subjects taught in the first year of the career and teachers of the discipline Health Research Methodology. Results: an update strategy was designed in search and retrieval of scientific information to develop computer skills in the first year of the Medicine degree. With three stages: Planning, execution and evaluation. Planning to transmit basic knowledge in the use of the Infomed portal and its resources. The execution is materialized with theoretical-practical activities related to the search and retrieval of scientific information. In the third stage, the updating in search and recovery of scientific information is evaluated in a comprehensive way. Conclusions: the strategy prepares students in the search and retrieval of scientific information, which develops computer knowledge and skills, according to the demands of study plan E in the Medicine degree.

Knowledge discovery in databases para apoio à decisão em atividades vinculadas à enfermagem / Knowledge discovery in databases para apoyar la decisión en actividades relacionadas con la enfermería / Knowledge discovery in databases for the support to decision-making in nursing-related activities

RESUMO Objetivo: relatar experiências de estratégias do uso da mineração de dados em dois cenários de práticas de Enfermagem. Descrição da experiência: em ambas as experiências foi utilizado o algoritmo Apriori para descoberta de regras de associação e identificado as situações de exceção. A primeira experiência utilizou dados provenientes de óbitos infantis da região metropolitana de Curitiba - PR. Na segunda experiência utilizaram-se prontuários de pacientes atendidos por enfermeiros na classificação de risco em um hospital particular de Curitiba - PR. O primeiro estudo identificou 374 regras gerais e o segundo, 108 regras gerais, ambos com suas respectivas regras de exceção. Conclusão: a aplicação do Knowledge Discovery in Databases pode ser demonstrada e efetivada em dois cenários distintos, a fim de contribuir para a tomada de decisão pelo gestor. Espera-se que o relato reforce a importância do ensino da informática em Enfermagem como ferramenta de apoio à decisão.

RESUMEN Objetivo: reportar experiencias de estrategias de uso de minería de datos en dos escenarios de prácticas de enfermería. Descripción del experimento: en ambos experimentos se utilizó el algoritmo Apriori para descubrir reglas de asociación e identificar situaciones excepcionales. El primer experimento utilizó datos de muertes infantiles en la región metropolitana de Curitiba-PR. En el segundo experimento, se utilizaron los registros médicos de los pacientes atendidos por enfermeros en la clasificación de riesgo en un hospital privado de Curitiba-PR. El primer estudio identificó 374 reglas generales y el segundo 108 reglas generales, ambas con sus respectivas reglas de excepción. Conclusión: la aplicación del Knowledge Discovery in Databases se puede demostrar e implementar en dos escenarios diferentes, con el fin de contribuir a la toma de decisiones por parte del gerente. Se espera que el informe refuerce la importancia de la enseñanza de la informática en enfermería como herramienta de apoyo a la toma de decisiones.

ABSTRACT Objective: to report experiences of data mining use strategies in two Nursing practice settings. Description of the experience: in both experiences, the Apriori algorithm was used to discover association rules and to identify exception situations. The first experience used data from infant deaths in the metropolitan region of Curitiba, PR. In the second experience, medical records of patients assisted by nurses were used in the risk classification at a private hospital in Curitiba -PR. The first study identified 374general rules and the second, 108, both with their respective exception rules. Conclusion: the application of Knowledge Discovery in Databases can be demonstrated and carried out in two different settings, in order to contribute to decision-making by the manager. It is expected that the report reinforces the importance of teaching Nursing Informatics as a decision-making support tool.

Indicadores bibliométricos de la producción científica peruana en plantas medicinales / Bibliometric indicators of peruvian scientific output about medicinal plants

RESUMEN Objetivo: Describir la producción científica sobre plantas medicinales con, al menos, un autor con filiación peruana publicada entre el 2000 y el 2019. Materiales y métodos: Se realizó un estudio bibliométrico mediante una búsqueda sistemática en la base de datos Scopus, de donde se seleccionaron artículos originales o comunicaciones breves sobre plantas medicinales que tuvieran, al menos, un autor con una filiación institucional peruana. Se describen las características de las publicaciones, instituciones, países y autores que participaron en estas investigaciones. Se calculó la proporción de colaboración internacional, el índice de transitoriedad, y las redes de colaboración institucional y de coautoria. Resultados: Se incluyeron 200 artículos originales publicados en 83 revistas, con una tendencia creciente, aunque irregular. La institución más productiva fue la Universidad Nacional Mayor de San Marcos, y la revista en la que más se publicó fue Journal of Ethnopharmacology. Las redes de autoría y de colaboración institucional mostraron la influencia de la colaboración internacional en estas publicaciones (53,0%). Conclusiones: La producción científica peruana sobre plantas medicinales tiene una tendencia creciente, se concentra en ámbitos académicos universitarios y se publica en revistas de alto impacto, debido, en parte, al alto nivel de cooperación internacional existente.

ABSTRACT Objective: To describe the scientific output on medicinal plants published between 2000 and 2019 with at least one author with Peruvian affiliation. Materials and methods: A bibliometric study was carried out by conducting a systematic search in the Scopus database, from which original articles or short communications on medicinal plants that had at least one author with Peruvian institutional affiliation were selected. The characteristics of the publications, institutions, countries and authors who participated in this research are described. The ratio of international collaboration, the transience index, and the institutional and co-authorship collaboration networks were calculated. Results: A total of 200 original articles published in 83 journals were included. The quantity of articles showed an increasing, though irregular trend during the studied period. The most productive institution was the Universidad Nacional Mayor de San Marcos, and the journal in which most of the articles were published was the Journal of Ethnopharmacology. Authorship and institutional collaboration networks showed the influence of international collaboration in these publications (53.0%). Conclusions: Peruvian scientific output on medicinal plants shows an increasing trend, observed mainly in academic university settings. The articles are published on high-impact journals, due in part to the high level of international cooperation.

Extent of Left Atrial Ablation Lesions and Atrial Fibrillation Recurrence after Catheter Ablation - A Systematic Review and Meta-Analysis / A Extensão das Lesões de Ablação no Átrio Esquerdo e a Recorrência de Fibrilação Atrial após Ablação por Cateter - Uma Revisão Sistemática e Metanálise

Abstract Background: Atrial fibrillation (AF) is known to induce atrial remodeling, which promotes fibrosis related to arrhythmogenesis. Accordingly, since scars induced by catheter ablation (CA) can reduce unablated fibrotic areas, greater extent of left atrial (LA) scarring may be associated with less AF recurrence after CA. Objectives: This study aims to investigate, through systematic review and meta-analysis, whether the amount of LA scarring, seen on late gadolinium enhancement magnetic resonance imaging, is associated with less AF recurrence after CA. Methods: The recommendations of the MOOSE guideline were followed. Database search was conducted in PubMed and Cochrane Central Register of Controlled Trials (comentário 1) until January 2019 (comentário 2). Two authors performed screening, data extraction, and quality evaluation. All studies were graded as good quality. A funnel plot was generated, showing no publication bias. Statistical significance was defined as p value < 0.05. Results: Eight observational studies were included in the systematic review, four of which were included in the meta-analysis. Six of the eight studies included in the systematic review showed that greater extension of LA scarring is associated with less AF recurrence after CA. Meta-analysis showed that greater extension of LA scarring is associated with less AF recurrence (SMD = 0.52; 95% CI 0.27 - 0.76; p < 0.0001). Conclusion: Greater extension of LA scarring is possibly associated with less AF recurrence after CA. Randomized studies that explore ablation methods based on this association are fundamental.

Resumo Fundamento: A fibrilação atrial (FA) é conhecida por induzir o remodelamento atrial, que promove fibrose, provocando, por sua vez, mais arritmogênese. Dessa forma, visto que as cicatrizes induzidas pela ablação por cateter (AC) podem reduzir as áreas fibróticas, uma maior extensão de cicatrizes do átrio esquerdo (AE) pode estar associada a uma menor recorrência da FA após AC. Objetivos: Por meio de revisão sistemática e metanálise, o presente estudo visa investigar se a extensão total de cicatriz do AE, visualizada na ressonância magnética com realce tardio de gadolínio após a ablação, está associada a uma menor recorrência de FA após AC. Métodos: Foram seguidas as recomendações das diretrizes MOOSE. A busca foi realizada nas bases de dados PubMed e Cochrane Central Register of Controlled Trials até Janeiro de 2019. Dois autores realizaram triagem, extração de dados e avaliação da qualidade dos estudos. Em relação à qualidade, todos os estudos foram classificados como bons. Foi gerado um gráfico de funil, o qual não mostrou viés de publicação. Foi adotado nível de significância p < 0,05. Resultados: Oito estudos observacionais foram incluídos na revisão sistemática, dos quais quatro foram incluídos na metanálise. Dos oito estudos incluídos na revisão, seis mostraram que maior extensão de cicatrização do AE está associada a uma menor recorrência de FA após AC. A metanálise também demonstrou que maior extensão de cicatrização do AE está associada a uma menor recorrência de FA (SMD = 0,52; IC 95% 0,27 - 0,76; p < 0,0001). Conclusão: Uma maior extensão de cicatrização do AE está possivelmente associada a uma menor recorrência de FA após AC. Estudos randomizados que explorem métodos de ablação baseados nessa associação são fundamentais.

Misdiagnosis of iatrogenic botulinum toxin poisoning:one case report and review of the literature / 中国基层医药

Objective To report 1 case of iatrogenic botulinum poisoning misdiagnosed as myasthenia gravis,to discuss the clinical manifestation,distinguishing feature and prognosis of iatrogenic botulinum poisoning combined with literature.Methods We briefly introduced one patient with botulinum toxin poisoning misdiagnosed as myasthenia gravis.A 26-year old female was admitted in June 2017 in Gaochun People's Hospital of Nanjing,who received two injections of botulinum toxin 500 U for a short period of time due to cosmetic needs,then she suffered from fatigue,chest distress,eyelid ptosis and other symptoms.The patient was once misdiagnosed as myasthenia gravis,but the results of neostigmine test and repeated nerve stimulation examination were negative.After careful examination of the body (mandibular swelling) and repeated medical history requiring,the final diagnosis was clarified.After the treatment such as fluid infusion for 10 days,her discomforts were relieved.The literature was retrieved from "US National Library of Medicine National Institutes of Health (Pubmed) "," China National Knowledge Infrastructure (CNKI)" and "Wanfang Medicine Data China Information",a total of 17 articles were included in the analysis,including 30 effective cases.We analyzed the general characteristics,clinical manifestations and prognosis of botulinum toxin injection.Results Of the 30 cases,28 cases (96.7％) were female,2 cases (3.0％) were male,aged from 3 to 80 years old.Most of them were botulinum toxin type A,except 2 cases unknown.The clinical onset began from the injection day to 3 weeks after injection.The duration of the disease lasted from 10 days to 6 months.Most of the prognosis was good after treatment.Conclusion Careful attention should be paid to the serious reaction of botulinum toxin to ensure safe medication use.

Progress in diagnosis and treatment of pancreatic tuberculosis / 中国基层医药

Pancreatic tuberculosis is a chronic and specific disease of the pancreas, which is rare in clinic.Pancreatic tuberculosis accounts for less than 5% of general miliary tuberculosis.This disease is often secondary to tuberculosis in other parts of the body.Because of the lack of awareness of pancreatic tuberculosis, it is easy to be misdiagnosed as pancreatic cancer.In the past, there were reports of pancreatic tuberculosis misdiagnosed as pancreatic cancer and then underwent pancreaticoduodenectomy treatment.In clinical practice, most of the cases of pancreatic tuberculosis were confirmed by during operation or postoperative pathology.In recent years, with the increase of the incidence of tuberculosis, the reports of pancreatic tuberculosis have also increased.Therefore, the study reviewed the literature of pancreatic tuberculosis in recent years in order to improve the understanding of pancreatic tuberculosis by the medical workers.

Progress in diagnosis and treatment of pancreatic tuberculosis / 中国基层医药

Pancreatic tuberculosis is a chronic and specific disease of the pancreas ,which is rare in clinic. Pancreatic tuberculosis accounts for less than 5% of general miliary tuberculosis.This disease is often secondary to tuberculosis in other parts of the body.Because of the lack of awareness of pancreatic tuberculosis ,it is easy to be misdiagnosed as pancreatic cancer.In the past,there were reports of pancreatic tuberculosis misdiagnosed as pancreatic cancer and then underwent pancreaticoduodenectomy treatment .In clinical practice,most of the cases of pancreatic tuberculosis were confirmed by during operation or postoperative pathology.In recent years,with the increase of the incidence of tuberculosis,the reports of pancreatic tuberculosis have also increased.Therefore,the study reviewed the literature of pancreatic tuberculosis in recent years in order to improve the understanding of pancreatic tuberculosis by the medical workers.